CKD・CVD地域連携包括医療学講座
Department of Chronic Kidney Disease (CKD) and Cardiovascular Disease (CVD)

業績

2024年

  1. Yoshifuji H, Nakaoka Y, Uchida HA, Sugihara T, Watanabe Y, Funakoshi S, Isobe M, Harigai M; Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS). Organ Damage and Quality of Life in Takayasu Arteritis - Evidence From a National Registry Analysis. Circ J. 2024 Feb 22;88(3):285-294.
  2. Katayama K, *Uchida HA, Takehara A, Wada J. A Case of Pseudoxanthoma Elasticum with juvenile-onset hypertension. In Press to Internal Medicine
  3. Nakanoh H, Takeuchi H, Morimoto S, Terajima Y, Okamoto S, Onishi Y, Tanaka K, Katsuyama T, Tsuji K, Matsumoto Y, Tanabe K, Morinaga H, Uka M, Tomita K, Uchida HA, Hiraki T, Wada J. A case of successful treatment for life threatening recurrent non-traumatic rectus sheath hematoma in microscopic polyangiitis with rapidly progressive glomerulonephritis. In Press to Internal Medicine
  4. Abe Y, Fujii T, Miyawaki Y, Sugihara T, Uchida HA, Maejima Y, Watanabe Y, Hashimoto T, Miyamae T, Nakaoka Y, Harigai M, Tamura N. The real-word clinical decisions of physicians in the management of Takayasu arteritis and giant cell arteritis in Japan: A cross-sectional web-questionnaire survey. In Press to Mod Rheumatol

2023年

  1. Matsuoka-Uchiyama N, Tsuji K, Takahashi K, Fukushima K, Takeuchi H, Kitamura S, Inagaki K, Uchida HA, Wada J, Association between urinary creatinine excretion and hypothyroidism in patients with chronic kidney disease. Diagnostics (Basel). 2023 Feb 10;13(4):669
  2. Tanaka K, Sugiyama H, Morinaga H, Kitagawa M, Kano Y, Onishi Y, Mise K, Tanabe K, Uchida HA, Wada J. Serum sCD40L and IL-31 in Association with Early Phase of IgA Nephropathy. Journal of Clinical Medicine. 2023 Mar 3;12(5):2023.
  3. Uchida HA, Onishi Y, Maeshima Y, Okuyama Y, Otaka N, Ujike H, Tanaka K, Takeuchi H, Tsuji K, Kitagawa M, Tanabe K, Morinaga H, Kinomura M, Kitamura S, Sugiyama H, Ota K, Maruyama K, Hiramatsu M, Oshiro Y, Morioka S, Takiue K, Omori K, Fukushima M, Gamou N, Hirata H, Sato R, Makino H, Wada J. The effect of medical cooperation in the CKD patients: 10-year multicenter cohort study. Journal of Personalized Medicine. 2023, 13, 582
  4. Sugihara T, Yoshifuji H, Uchida HA, Maejima Y, Watanabe Y, Tanemoto K, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Niiro H, Ishii T, Nakaoka Y, Harigai M. Establishing clinical remission criteria for giant cell arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis. Modern Rheumatology. 2023 May 24:road046.
  5. Goyama T, Fujii Y, Muraoka G, Nakatani T, Ousaka D, Imai Y, Kuwada N, Tsuji T, Shuku T, Uchida HA, Nishibori M, Oozawa S, Kasahara S. Comprehensive hemocompatibility analysis on the application of diamond-like carbon to ePTFE artificial vascular prosthesis. Scientific Report. 2023 May 24;13(1):8386
  6. Subramanian V, Uchida HA, Miyoshi T. Editorial: Advanced research on abdominal and thoracic aortic aneurysms: new insights into molecular mechanisms. Front Cardiovasc Med. 2023 Oct 19;10:1304498.
  7. Tsuji K, Nakanoh H, Takahashi K, Morita T, Sang Y, Fukushima K, Matsuoka-Uchiyama N, Onishi Y, Uchida HA, Kitamura S, Wada J. Kidney Veno-Muscular Characteristics and Kidney Disease Progression: A Native Kidney-Biopsy Study. Kidney Med. 2023 Oct 5;5(12):100733.
  8. Mori A, Saito Y, Nakamura K, Iida T, Akagi S, Yoshida M, Taniyama M, Miyoshi T, Ito H. Microcalcification and 99mTc-Pyrophosphate Uptake without Increased Bone Metabolism in Cardiac Tissue from Patients with Transthyretin Cardiac Amyloidosis. Int J Mol Sci. 2023 Jan 18;24(3):1921.
  9. Akagi S, Nakamura K, Kondo M, Hirohata S, Udono H, Nishida M, Saito Y, Yoshida M, Miyoshi T, Ito H. Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial Hypertension J Clin Med. 2023 Jul 31;12(15):5028.
  10. Saito Y, Nose N, Iida T, Akazawa K, Kanno T, Fujimoto Y, Sasaki T, Akehi M, Higuchi T, Akagi S, Yoshida M, Miyoshi T, Ito H, Nakamura K. In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging. Front Cardiovasc Med. 2023 Sep 7;10:1261330.

2022年

  1. Matsuoka-Uchiyama N, Uchida HA, Okamoto S, Onishi Y, Katayama K, Tsuchida-Nishiwaki M, Takeuchi H, Takemoto R, Hada Y, Umebayashi R, Kurooka N, Tsuji K, Eguchi J, Nakajima H, Shikata K, Wada J. The Association of Postprandial Triglyceride Variability with Renal Dysfunction and Microalbuminuria in Patients with Type 2 Diabetic Mellitus: A Retrospective and Observational Study. Journal of Diabetes Research. 2022 Jan 10;2022:3157841.
  2. Umebayashi R, Uchida HA, Matsuoka-Uchiyama N, Sugiyama H, Wada J. Prevalence of Chronic Kidney Disease and Variation of Its Risk Factors by the Regions in Okayama Prefecture. Journal of Personalized Medicine. 2022 Jan 12;12(1):97.
  3. Ichikawa K, Miyoshi T, Osawa K, Miki T, Toda H, Ejiri K, Yoshida M, Nakamura K, Morita H, Ito H. Incremental prognostic value of non-alcoholic fatty liver disease over coronary computed tomography angiography findings in patients with suspected coronary artery disease. Eur J Prev Cardiol. 2022 Feb 9;28(18):2059-2066.
  4. Fukushima K, Uchida HA, Fuchimoto Y, Mifune T, Watanabe M, Tsuji K, Tanabe K, Kinomura M, Kitamura S, Miyamoto Y, Wada S, Koyanagi T, Sugiyama H, Kishimoto T, Wada J. Silica-associated systemic lupus erythematosus with lupus nephritis and lupus pneumonitis: A case report and a systematic review of the literature. Medicine (Baltimore). 2022 Feb 18;101(7):e28872.
  5. Ogura S, Nakamura K, Morita H, Nakagawa K, Nishii N, Akagi S, Toh N, Takaya Y, Yoshida M, Miyoshi T, Watanabe A, Ito H. Fragmented QRS as a predictor of cardiac events in patients with cardiac sarcoidosis. Journal of Cardiology. 2022 Mar;79(3):446-452.
  6. Onishi Y, Mise K, Kawakita C, Uchida HA, Sugiyama H, Sugawara R, Yamaguchi S, Yoshida M, Mitsuhashi T, Yamada M, Hirabayashi J, Wada J. Development of Urinary Diagnostic Biomarker for IgA Nephropathy by Lectin Microarray. American Journal of Nephrology. 2022;53(1):10-20.
  7. Kurooka N, Eguchi J, Murakami K, Kamei S, Kikutsuji T, Sasaki S, Seki A, Yamaguchi S, Nojima I, Watanabe M, Higuchi C, Katayama A, Uchida HA, Nakatsuka A, Shikata K, Wada J. Circulating GPIHBP1 levels and microvascular complications in patients with type 2 diabetes: A cross-sectional study. Journal of Clinical Lipidology. 2022 Mar-Apr;16(2):237-245.
  8. Miyoshi T, Nakamura K, Amioka N, Hatipoglu OF, Yonezawa T, Saito Y, Yoshida M, Akagi S, Ito H. LCZ696 ameliorates doxorubicin-induced cardiomyocyte toxicity in rats. Scientific Report. 2022 Mar 23;12(1):4930.
  9. Nakamura K, Miyoshi T, Yoshida M, Akagi S, Saito Y, Ejiri K, Matsuo N, Ichikawa K, Iwasaki K, Naito T, Namba Y, Yoshida M, Sugiyama H, Ito H. Pathophysiology and Treatment of Diabetic Cardiomyopathy and Heart Failure in Patients with Diabetes Mellitus. International Journal of Molecular Science. 2022 Mar 25;23(7):3587.
  10. Saito Y, Nakamura K, Yoshida M, Sugiyama H, Akagi S, Miyoshi T, Morita H, Ito H. Enhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther. 2022 Apr 1;13(1):141.
  11. Hiramatsu-Asano S, Mukai T, Akagi T, Uchida HA, Fujita S, Nakano K, Morita Y. IL-17A promotes vascular calcification in an ex vivo murine aorta culture. Biochem Biophys Res Commun. 2022 May 14;604:83-87.
  12. Amioka N, Takaya Y, Nakamura K, Kondo M, Akazawa K, Ohno Y, Ichikawa K, Nakayama R, Saito Y, Akagi S, Miyoshi T, Yoshida M, Morita H, Ito H. Impact of shear wave dispersion slope analysis for assessing the severity of myocarditis. Scientific Report. 2022 May 24;12(1):8776.
  13. Amioka N, Miyoshi T, Yonezawa T, Kondo M, Akagi S, Yoshida M, Saito Y, Nakamura K, Ito H. Pemafibrate Prevents Rupture of Angiotensin II-Induced Abdominal Aortic Aneurysms. Front Cardiovasc Med. 2022 Jun 30;9:904215.
  14. Hada Y, Uchida HA, Umebayashi R, Yoshida M, Wada J. Cilostazol Attenuates AngII-Induced Cardiac Fibrosis in apoE Deficient Mice. International Journal of Molecular Science. 2022 Aug 13;23(16):9065.
  15. Uchida HA, Takatsuka T, Hada Y, Umebayashi R, Takeuchi H, Shikata K, Subramanian V, Daugherty A, Wada J. Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice. Biomolecules. 2022 Aug 14;12(8):1117.
  16. Sugihara T, Nakaoka Y, Uchida HA, Yoshifuji H, Maejima Y, Watanabe Y, Amiya E, Tanemoto K, Miyata T, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Miyamae T, Niiro H, Ito S, Ishii T, Isobe M, Harigai M. Establishing clinical remission criteria and the framework of a treat-to-target algorithm for Takayasu arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour and Welfare for intractable vasculitis. Modern Rheumatology. 2022 Aug 20;32(5):930-937.
  17. Matsuoka-Uchiyama N, Tsuji K, Sang Y, Takahashi K, Fukushima K, Takeuchi H, Inagaki K, Uchida HA, Kitamura S, Sugiyama H, Wada J. The association between hypothyroidism and proteinuria in patients with chronic kidney disease: a cross-sectional study. Scientific Report. 2022 Sep 2;12(1):14999.
  18. Tsuji K, Kitamura S, Uchida HA, Wada J. Simulation for ultrasound-guided renal biopsy using boiled egg. Nephrology (Carlton). 2022 Sep;27(9):753-757.
  19. Sugihara T, Uchida HA, Yoshifuji H, Maejima Y, Naniwa T, Katsumata Y, Okazaki T, Ishizaki J, Murakawa Y, Ogawa N, Dobashi H, Horita T, Tanaka Y, Furuta S, Takeuchi T, Komagata Y, Nakaoka Y, Harigai M. Association between the patterns of large-vessel lesions and treatment outcomes in patients with large-vessel giant cell arteritis. Modern Rheumatology. 2022 Oct 11:roac122.
  20. Takeuchi H, Uchida HA, Katayama K, Matsuoka-Uchiyama N, Okamoto S, Onishi Y, Okuyama Y, Umebayashi R, Miyaji K, Kai A, Matsumoto I, Taniguchi K, Yamashita F, Emi T, Sugiyama H, Wada J. The Beneficial Effect of Personalized Lifestyle Intervention in Chronic Kidney Disease Follow-Up Project for National Health Insurance Specific Health Checkup: A Five-Year Community-Based Cohort Study. Medicina (Kaunas). 2022 Oct 26;58(11):1529.
  21. Uchida HA, Nakajima H, Hashimoto M, Nakamura A, Nunoue T, Murakami K, Hosoya T, Komoto K, Taguchi T, Akasaka T, Shiosakai K, Sugimoto K, Wada J; EX-DKD investigators. Efficacy and Safety of Esaxerenone in Hypertensive Patients with Diabetic Kidney Disease: A Multicenter, Open-Label, Prospective Study. Advance in Therapy. 2022 Nov;39(11):5158-5175.
  22. Uchiyama-Matsuoka N, Tsuji K, Uchida HA, Kitamura S, Itoh Y, Nishiyama Y, Morimoto E, Fujisawa S, Terasaka T, Hara T, Ogura-Ochi K, Inagaki K, Wada J. Masked CKD in hyperthyroidism and reversible CKD status in hypothyroidism. Frontier Endocrinology (Lausanne). 2022 Nov 8;13:1048863.
  23. Kageyama S, Hayashi R, Uchida HA. Case of clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) due to Legionella BMJ Case Report. 2022 Dec 30;15(12):e252994.

2021年

  1. Cooper HA, Cicalese S, Kawai T, Preston KJ, Kasahara S, Uchida HA, Otaka N, Choi ET, Scalia R, Rizzo V, Eguchi S, Inhibition of Mitochondrial Fission Prevents Abdominal Aortic Aneurysm Development in Mice. Cardiovascular Research 2021 Feb 22;117(3):971-982
  2. Otaka N, Uchida HA, Okuyama M, Hada Y, Onishi Y, Kakio Y, Takeuchi H, Umebayashi R, Tanabe K, Subramanian V, Daugherty A, Sato Y, Wada J, Exogenous Vasohibin-2 Aggravates Development of Angiotensin II-induced Ascending Aortic Aneurysms But Not Abdominal Aortic Aneurysms Nor Atherosclerosis in Apolipoprotein E-Deficient Mice. American Journal of Hypertension. 2021 May 22;34(5):467-475.
  3. Muniappan L, Javidan A, Jiang W, Moorleghen JJ, Balakrishnan A, Howatt DA, Uchida HA, Saido T, Subramanian V. Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2021 May 5;41(5):1694-1709.
  4. Hada Y, Uchida HA, Wada J, Fisetin Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Macrophage. BioMed Research International. 2021 Apr 13;2021:5570885.
  5. Mise K, Imamura M, Yamaguchi S, Watanabe M, Higuchi C, Katayama A, Miyamoto S, Uchida HA, Nakatsuka A, Eguchi J, Hida K, Nakato T, Tone A, Teshigawara S, Matsuoka T, Kamei S, Murakami K, Shimizu I, Miyashita K, Ando S, Nunoue T, Yoshida M, Yamada M, Shikata K, Wada J, Novel Urinary Glycan Biomarkers Predict Cardiovascular Events in Patients with Type 2 Diabetes: A Multicenter Prospective Study with 5-year Follow up (U-CARE Study 2). Frontiers in Cardiovascular Medicine 2021 May 24;8:668059.
  6. Tsuchida-Nishiwaki M, Uchida HA, Takeuchi H, Nishiwaki N, Maeshima Y, Saito C, Sugiyama H, Wada J, Narita I, Watanabe T, Matsuo S, Makino H, Hishida A, Yamagata K, Association of blood pressure and renal outcome in patients with chronic kidney disease; a post hoc analysis of FROM-J study. Scientific Reports. 2021 Jul 22;11(1):14990.
  7. Takemoto R, Uchida HA, Toda H, Okada K, Otsuka F, Ito H, Wada J, Total Vascular Resistance, Augmentation Index and Augmentation Pressure increase in patients with peripheral artery disease. Medicine (Baltimore) 2021 Aug 13;100(32):e26931
  8. Ichikawa K, Miyoshi T, Osawa K, Miki T, Toda H, Ejiri K, Yoshida M, Nanba Y, Yoshida M, Nakamura K, Morita H, Ito H. Prognostic value of non-alcoholic fatty liver disease for predicting cardiovascular events in patients with diabetes mellitus with suspected coronary artery disease: a prospective cohort study. Cardiovascular Diabetology. 2021 Jan 7;20(1):8.
  9. Iwano T, Toda H, Nakamura K, Shimizu K, Ejiri K, Naito Y, Mori H, Masuda T, Miyoshi T, Yoshida M, Hikasa Y, Morimatsu H, Ito H; MAMACARI Investigators. Preventative effects of bisoprolol transdermal patches on postoperative atrial fibrillation in high-risk patients undergoing non-cardiac surgery: A subanalysis of the MAMACARI study. Journal of Cardiology. 2021 Nov;78(5):349-354
  10. Amioka N, Nakamura K, Kimura T, Ohta-Ogo K, Tanaka T, Toji T, Akagi S, Nakagawa K, Toh N, Yoshida M, Miyoshi T, Nishii N, Watanabe A, Asano R, Ogo T, Nakaoka Y, Morita H, Yanai H, Ito H. Pathological and clinical effects of interleukin-6 on human myocarditis. Journal of Cardiology. 2021 Aug;78(2):157-165.
  11. Nakayama R, Takaya Y, Nakamura K, Kondo M, Kobayashi K, Ohno Y, Amioka N, Akagi S, Yoshida M, Miyoshi T, Ito H. Efficacy of shear wave elastography for evaluating right ventricular myocardial fibrosis in monocrotaline-induced pulmonary hypertension rats. Journal of Cardiology. 2021 Jul;78(1):17-23.
  12. Nakamura K, Akagi S, Ejiri K, Yoshida M, Miyoshi T, Sakaguchi M, Amioka N, Suastika LOS, Kondo M, Nakayama R, Takaya Y, Higashimoto Y, Fukami K, Matsubara H, Ito H. Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats. Journal of Cardiology. 2021 Jul;78(1):12-16.
  13. Takaya Y, Nakamura K, Nakayama R, Ohtsuka H, Amioka N, Kondo M, Akazawa K, Ohno Y, Ichikawa K, Saito Y, Akagi S, Yoshida M, Miyoshi T, Ito H. Efficacy of shear wave elasticity for evaluating myocardial hypertrophy in hypertensive rats. Scientific Reports. 2021 Nov 24;11(1):22812.

2020年

  1. Isobe M, Amano K, Arimura Y, Ishizu A, Ito S, Kaname S, Kobayashi S, Komagata Y, Komuro I, Komori K, Takahashi K, Tanemoto K, Hasegawa H, Harigai M, Fujimoto S, Miyazaki T, Miyata T, Yamada H, Yoshida A, Wada T, Inoue Y, Uchida HA, Ota H, Okazaki T, Onimaru M, Kawakami T, Kinouchi R, Kurata A, Kosuge H, Sada KE, Shigematsu K, Suematsu E, Sueyoshi E, Sugihara T, Sugiyama H, Takeno M, Tamura N, Tsutsumino M, Dobashi H, Nakaoka Y, Nagasaka K, Maejima Y, Yoshifuji H, Watanabe Y, Ozaki S, Kimura T, Shigematsu H, Yamauchi-Takihara K, Murohara T, Momomura SI; JCS Joint Working Group. JCS 2017 Guideline on Management of Vasculitis Syndrome - Digest Version. Circulation Journal. 2020 Jan 24;84(2):299-35.
  2. Ogawa-Akiyama A, Sugiyama H, Kitagawa M, Tanaka K, Kano Y, Mise K, Otaka N, Tanabe K, Morinaga H, Kinomura M, Uchida HA, Wada J, Podocyte autophagy is associated with foot process effacement and proteinuria in patients with minimal change nephrotic syndrome. PLoS One. 2020 Jan 24;15(1):e0228337.
  3. Sugihara T, Hasegawa H, Uchida HA, Yoshifuji H, Watanabe Y, Amiya E, Maejima Y, Konishi M, Murakawa Y, Ogawa N, Furuta S, Katsumata Y, Komagata Y, Naniwa T, Okazaki T, Tanaka Y, Takeuchi T, Nakaoka Y, Arimura Y, Harigai M, Isobe M. Associated factors of poor treatment outcomes in patients with giant cell arteritis: clinical implication of large vessel lesions. Arthritis Research & Therapy 2020 Apr 7;22(1):72.
  4. Takeuchi H, Uchida HA, Wada J. Frailty raises as a new target in patients with chronic hemodialysis in any country and the problem we should solve. Journal of Clinical Trials 10:414.
  5. Akagi T, Mukai T, Mito T, Kawahara K, Tsuji S, Fujita S, Uchida HA, Morita Y, The effect of angiotensin II on bone erosion and systemic bone loss in TNF-mediated arthritis mice. International Journal of Molecular Sciences 2020 Jun 10;21(11):4145.
  6. Hada Y, Uchida HA, Otaka N, Onishi Y, Okamoto S, Nishiwaki M, Takemoto R, Takeuchi H, Wada J, The Protective Effect of Chlorogenic Acid on Vascular Senescence via Nrf2/HO-1 Pathway. International Journal of Molecular Sciences 2020 Jun 25;21(12):4527.
  7. Nojima I, Eikawa S, Tomonobu N, Hada Y, Kajitani N, Teshigawara S, Miyamoto S, Tone A, Uchida HA, Nakatsuka A, Eguchi J, Shikata K, Udono H, Wada J, Dysfunction of CD8+PD-1+ T cells in type 2 diabetes caused by the impairment of metabolism-immune axis. Scientific Report. 2020 Sep 10;10(1):14928.
  8. Matsuoka-Uchiyama N, Tsuji K, Fukushima K, Kitamura S, Uchida HA, Sugiyama H, Takahashi N, Iwano M, Wada J. Tubulointerstitial Nephritis Cases With IgM-Positive Plasma Cells. Kidney International Report. 2020 Jun 18;5(9):1576-1580.
  9. Yoshinaga K, Araki M, Wada K, Maruyama Y, Mitsui Y, Sadahira T, Kubota R, Nishimura S, Kobayashi Y, Takeuchi H, Tanabe K, Kitagawa M, Morinaga H, Uchida HA, Kitamura S, Sugiyama H, Wada J, Watanabe M, Watanabe T, Nasu Y. Low-dose rituximab induction therapy is effective in immunological high-risk renal transplantation without increasing cytomegalovirus infection. International Journal of Urology. 2020 Dec;27(12):1136-1142..
  10. Hada Y, Uchida HA, Mukai T, Kojima F, Yoshida M, Takeuchi H, Kakio Y, Otaka N, Morita Y, Wada J, Inhibition of Interleukin-6 Signaling Attenuates Aortitis, Left Ventricular Hypertrophy and Arthritis in Interleukin-1 Receptor Antagonist Deficient Mice. Clinical Sciences (London). 2020 134 2771–2787.
  11. Ogura S, Nakamura K, Morita H, Toh N, Nakagawa K, Yoshida M, Watanabe A, Nishii N, Miyoshi T, Ito H. New Appearance of Fragmented QRS as a Predictor of Ventricular Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy. Circulation Journal. 2020 Feb 25;84(3):487-494.
  12. Toda H, Nakamura K, Shimizu K, Ejiri K, Iwano T, Miyoshi T, Nakagawa K, Yoshida M, Watanabe A, Nishii N, Hikasa Y, Hayashi M, Morita H, Morimatsu H, Ito H; MAMACARI Investigators. Effects of Bisoprolol Transdermal Patches for Prevention of Perioperative Myocardial Injury in High-Risk Patients Undergoing Non-Cardiac Surgery - Multicenter Randomized Controlled Study. Circulation Journal. 2020 Mar 25;84(4):642-649.
  13. Hatipoglu OF, Miyoshi T, Yonezawa T, Kondo M, Amioka N, Yoshida M, Akagi S, Nakamura K, Hirohata S, Ito H. Deficiency of CD44 prevents thoracic aortic dissection in a murine model. Scientific Report. 2020 Apr 22;10(1):6869.
  14. Yoshida M, Nakamura K, Miyoshi T, Yoshida M, Kondo M, Akazawa K, Kimura T, Ohtsuka H, Ohno Y, Miura D, Ito H. Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet. Cardiovasc Diabetolology. 2020 Sep 26;19(1):149.
  15. Miki T, Miyauchi S, Miyoshi T, Yoshida M, Ichikawa K, Soh J, Nakamura K, Kiura K, Kanazawa S, Toyooka S, Ito H. Chemoradiation therapy for non-small cell lung cancer exacerbates thoracic aortic calcification determined by computed tomography. Heart Vessels. 2020 Oct;35(10):1401-1408.

2019年

  1. Okuyama Y, Uchida HA, Iwahori T, Segawa H, Kato A, Takeuchi H, Kakio Y, Umebayashi R, Kitagawa M, Sugiyama H, Miura K, Ueshima T, Wada J. The relationship of the repeated measurement of casual and 24-hour urinary sodium-to-potassium ratio in patients with chronic kidney disease. Journal of Human Hypertension. 2019 Apr;33(4):286-297.
  2. Umebayashi R, Uchida HA, Okuyama Y, Kakio Y, Hanayama Y, Shikata K, Wada J. The clinical efficacy of angiotensin II type1 receptor blockers on inflammatory markers in patients with hypertension: a multicenter randomized-controlled trial; MUSCAT-3 study. Biomarkers. 2019 24:3, 255-261.
  3. Matsuoka N, Uchida HA, Hara Y, Matsuda H. Osteomalacia and Fanconi Syndrome Induced by Adefovir. Internal Medicine. 2019 Jun 1;58(11):1659.
  4. Toda H, Uchida HA, Nakamura K, Takeuchi H, Kinomura M, Nakagawa K, Watanabe A, Miyoshi T, Nishii N, Morita H, Wada J, Ito H. Combination of percutaneous transluminal renal angioplasty and angiotensin-converting-enzyme inhibitor can reduce proteinuria in two patients with bilateral renal artery disease. Internal Medicine. 2019 Jul 1;58(13):1917-1922.
  5. Mifune T, Uchida HA, Fukushima K, Watanabe M, Ouchi C, Mise K, Kawakita C, Kano Y, Onishi A, Toma T, Eguchi J, Wada N, Ikeda F, Sasaki E, Suganami Y, Kishida M, Sugiyama H, Okada H, Wada J. A case of autoimmune polyglandular syndrome type 3 associated with systemic lupus erythematosus 8 years after diagnosis. Acta Medica Okayama 2019 Aug;73(4):367-372.
  6. Uchida HA, Okuyama M, Hada Y, Kakio Y, Otaka N, Umebayashi R, Tanabe K, Fujii Y, Kasahara S, Subramanian V, Daugherty A, Sato Y, Wada J. Exogenous Vasohibin-2 Exacerbates Angiotensin II-induced Ascending Aortic Dilatation, Circulation Reports. 2019; 1: 155-161
  7. Sakamoto S, Maimaiti M, Minhui X, Kamada S, Yamada Y, Kito H, Matsumoto H, Takeuchi N, Higuchi K, Uchida HA, Komiya A, Nagata M, Nakatsu H, Matsuyama H, Akakura K, Ichikawa T. Higher serum testosterone levels associated with favorable prognosis in enzalutamide and abiraterone-treated castration-resistant prostate cancer. Journal of Clinical Medicine. 2019, 8(4), 489; pii: E489.
  8. Kakio Y, Uchida HA, Takeuchi H, Okuyama Y, Umebayashi R, Watatani H, Maeshima Y, Sugiyama H, Wada J. Report of health checkup system for chronic kidney disease in general population in Okayama city: Effect of health guidance intervention on chronic kidney disease outcome. International Journal of Nephrology and Renovascular Disease 2019, 12:143-152
  9. Onishi A, Sugiyama H, Kitagawa M, Yamanari T, Tanaka K, Ogawa-Akiyama A, Kano Y, Mise K, Tanabe K, Morinaga H, Kinomura M, Uchida HA, Wada J. Urine 5MedC, a Marker of DNA Methylation, in the Progression of Chronic Kidney Disease. Disease Markers. 2019 Jul 1;2019:5432453.
  10. Onishi Y, Uchida HA, Takeuchi H, Kakio Y, Sugiyama H, Wada J, Shimada N, Tokumasu H, Fukushima M, Asano K. Impaired mental health status in patients with CKD is associated with eGFR decline. Nephrology (Carlton). 2019 Sep;24(9):926-932
  11. Umebayashi R, Uchida HA, Wada J. The Aging Population and Research into Treatments for Abdominal Aortic Aneurysms. Acta Medica Okayama. 2019 Dec;73(6):475-477.
  12. Kimura T, Nakamura K, Miyoshi T, Yoshida M, Akazawa K, Saito Y, Akagi S, Ohno Y, Kondo M, Miura D, Wada J, Ito H. Inhibitory Effects of Tofogliflozin on Cardiac Hypertrophy in Dahl Salt-Sensitive and Salt-Resistant Rats Fed a High-Fat Diet. International Heart Journal. 2019 May 30;60(3):728-735.
  13. Miyoshi T, Osawa K, Ichikawa K, Suruga K, Miki T, Yoshida M, Nakagawa K, Toda H, Nakamura K, Morita H, Ito H. Emerging Role of Coronary Computed Tomography Angiography in Lipid-Lowering Therapy: a Bridge to Image-Guided Personalized Medicine. Current Cardiology Reports. 2019 Jun 21;21(8):72.
  14. Nakamura K, Akagi S, Ejiri K, Yoshida M, Miyoshi T, Toh N, Nakagawa K, Takaya Y, Matsubara H, Ito H. Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension. International Journal of Molecular Sciences. 2019 Nov 23;20(23):5885.
  15. Matsumi H, Nakamura K, Eguchi E, Miyoshi T, Nakagawa K, Nishii N, Watanabe A, Ueoka A, Yoshida M, Tokunaga N, Amioka N, Yamada N, Saito D, Morita H, Ogino K, Ito H; Ibara-AF Investigators. Low Consultation Rate of General Population with Atrial Fibrillation. International Heart Journal. 2019 Nov 30;60(6):1303-1307.
  16. Miyoshi T, Nakamura K, Miura D, Yoshida M, Saito Y, Akagi S, Ohno Y, Kondo M, Ito H. Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. Cardiology Journal. 2019;26(5):575-583.

2018年

  1. Takeuchi H, Uchida HA, Kakio Y, Okuyama Y, Okuyama M, Umebayashi R, Wada K, Sugiyama H, Sugimoto K, Rakugi H, Wada J. The Prevalence of Frailty and its Associated Factors in Japanese Hemodialysis Patients. Aging and Disease. 2018, 9 (2): 192-207.
  2. Uchida HA, Kitagawa M, Wada J. Impact of nocturnal blood pressure variability on renal arterioles. Hypertension Research. 2018 Jan;41(1):6-7.
  3. Kakio Y, Uchida HA, Kitagawa M, Arata Y, Kato A, Inoue-Torii A, Hinamoto N, Ogawa-Akiyama A, Sugiyama H, Wada J. IgA nephropathy complicated with X-linked thrombocytopenia: a case report. Acta Medica Okayama. 2018 Jun;72(3):301-307.
  4. Umebayashi R, Uchida HA, Kakio Y, Subramanian V, Daugherty A, Wada J. Cilostazol Attenuates AngII-induced Abdominal Aortic Aneurysms But Not Atherosclerosis in ApoE Deficient Mice, Arteriosclerosis, Thrombosis, and Vascular Biology. 2018 Mar;38:892-902.
  5. Okuyama M, Takeuchi H, Uchida HA, Kakio Y, Okuyama Y, Umebayashi R, Wada K, Sugiyama H, Sugimoto K, Rakugi H, Kasahara S, Wada J. Peripheral Artery Disease Is Associated with Frailty in Chronic Hemodialysis Patients. Vascular. 2018 Aug;26(4):425-431.
  6. Ogawa-Akiyama A, Sugiyama H, Kitagawa M, Tanaka K, Onishi A, Yamanari T, Morinaga H, Uchida HA, Nakamura K, Ito H, Wada J. The serum cystatin C level is significantly associated with the renal resistive index value in patients with chronic kidney disease. PLoS One. 2018 Mar 7;13(3): e0193695.
  7. Kajitani N, Uchida HA, Suminoe I, Kakio Y, Kitagawa M, Sato H, Wada J. Chronic kidney disease and carotid atherosclerosis are associated with symptomatic stroke. Journal of International Medical Research. 2018 Sep;46(9):3873-3883.
  8. Mise K, Imamura M, Yamaguchi S, Teshigawara S, Tone A, Uchida HA, Eguchi J, Nakatsuka A, Ogawa D, Yoshida M, Yamada M, Shikata K, Wada J. Identification of Novel Urinary Biomarkers for Predicting Renal Prognosis in Patients with Type 2 Diabetes by Glycan Profiling in a Multicenter Prospective Cohort Study: U-CARE Study 1. Diabetes Care. 2018 Aug;41(8):1765-1775.
  9. Umebayashi R, Uchida HA, Wada J. Abdominal aortic aneurysm in aged population. Aging (Albany NY). 2018 Dec 6;10(12):3650-3651.
  10. Kakio Y, Uchida HA, Takeuchi H, Okuyama Y, Okuyama M, Umebayashi R, Wada K, Sugiyama H, Sugimoto K, Rakugi H, Wada J. Diabetic Nephropathy Is Associated with Frailty in Patients with Chronic Hemodialysis. Geriatrics & Gerontology International. 2018 Dec;18(12):1597-1602.
  11. Saito Y, Nakamura K, Yoshida M, Sugiyama H, Takano M, Nagase S, Morita H, Kusano KF, Ito H. HCN4-Overexpressing Mouse Embryonic Stem Cell-Derived Cardiomyocytes Generate a New Rapid Rhythm in Rats with Bradycardia. International Heart Journal. 2018 May 30;59(3):601-606.
  12. Saito Y, Nakamura K, Nishi N, Igawa O, Yoshida M, Miyoshi T, Watanabe A, Morita H, Ito H. TRPM4 Mutation in Patients With Ventricular Noncompaction and Cardiac Conduction Disease. Circulation-Genomic and Precision Medicine. 2018 May;11(5):e002103
  13. Nakamura K, Sakaguchi M, Matsubara H, Akagi S, Sarashina T, Ejiri K, Akazawa K, Kondo M, Nakagawa K, Yoshida M, Miyoshi T, Ogo T, Oto T, Toyooka S, Higashimoto Y, Fukami K, Ito H. Crucial role of RAGE in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension. PLoS One. 2018 Sep 4;13(9):e0203046.

2017年

  1. Wada K, Uchida HA, Wada Y. Effectiveness of Jidabokuippo (Traditional Japanese Kampo Medicine) on Venous Thrombosis and Hematoma after Percutaneous Femoral Catheterization. Renal Replacement Therapy 2017 3:3 doi: 10.1186/s41100-016-0086-3.
  2. Kakio Y, Uchida HA, Umebayashi R, Takeuchi H, Okuyama Y, Hanayama Y, Wada J. Practical Efficacy of Olmesartan versus Azilsartan in Patients with Hypertension ~ Multicenter Randomized Control Trial ~ MUSCAT-4 Study. Blood Pressure Monitoring. 2017 Apr;22(2):59-67.
  3. Wada K, Uchida HA, Hakoda T, Wada Y. A Case of Poor Glycemic Control attributable to Insulin Antibody in a Fulminant Type 1 Diabetes Patient under Hemodialysis: Successful Treatment with Double Filtration Plasmapheresis and Prednisolone. Renal Replacement Therapy 2017 3:14 DOI: 10.1186/s41100-017-0096-9
  4. Tanaka K, Kitagawa M, Onishi A, Yamanari T, Ogawa-Akiyama A, Mise K, Inoue T, Morinaga H, Uchida HA, Sugiyama H, Wada J. Arterial Stiffness is an Independent Risk Factor for Anemia After Percutaneous Native Kidney Biopsy. Kidney & Blood Pressure Research. 2017;42(2):284-293.
  5. Nakamura K, Matsubara H, Akagi S, Sarashina T, Ejiri K, Kawakita N, Yoshida M, Miyoshi T, Watanabe A, Nishii N, Ito H. Nanoparticle-Mediated Drug Delivery System for Pulmonary Arterial Hypertension. Journal of Clinical Medicine 2017 Apr 29;6(5). pii: E48.
  6. Nakamura K, Miura D, Saito Y, Yunoki K, Koyama Y, Satoh M, Kondo M, Osawa K, Hatipoglu OF, Miyoshi T, Yoshida M, Morita H, Ito H. Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice. PLoS One. 2017 Aug 3;12(8):e0181009.
  7. Saito Y, Nakamura K, Miura D, Yunoki K, Miyoshi T, Yoshida M, Kawakita N, Kimura T, Kondo M, Sarashina T, Akagi S, Watanabe A, Nishii N, Morita H, Ito H. Suppression of Wnt Signaling and Osteogenic Changes in Vascular Smooth Muscle Cells by Eicosapentaenoic Acid. Nutrients. 2017 Aug 10;9(8). pii: E858.

2016年

  1. Howatt DA, Balakrishnan A, Moorleghen JJ, Muniappan L, Rateri DL, Uchida HA, Takano J, Saido T, Chishti AH, Baud L, Subramanian V, Leukocyte Calpain Deficiency Reduces AngiotensinII-induced Inflammation and Atherosclerosis but not Abdominal Aortic Aneurysms in Mice. Arterioscler Thromb Vasc Biol. 2016 May;36(5):835-45.
  2. Takeuchi H, Uchida HA, Okuyama Y, Wada J, The Acute idiopathic blue fingers: A young male with Achenbach`s syndrome. BMJ Case Rep. 2016 Apr 18;2016:10.1136/bcr-2016-214491.
  3. Uchida HA, Wada J, Makino H. The Possible Association of the Incidence of ESRD in the Patient with Diabetic Nephropathy with Salt Intake in the World. BMJ open e-letter 2016, Aug. http://bmjopen.bmj.com/content/3/12/e003733/reply#bmjopen_el_9924
  4. Terasaka T, Uchida HA, Umebayashi R, Tsukamoto K, Tanaka K, Kitagawa M, Sugiyama H, Tanioka H, Wada J. The possible involvement of intestine-derived IgA1: A case of IgA nephropathy associated with Crohn’s disease. BMC Nephrology. 2016 Sep 5;17(1):122.
  5. Takeuchi H, Okuyama M, Uchida HA, Kakio Y, Umebayashi R, Okuyama Y, Fujii Y, Ozawa S, Yoshida M, Oshima Y, Sano S, Wada J. Chronic Kidney Disease Is a Risk for Abdominal Aortic Aneurysm But Diabetes Mellitus Is a Protective Factor. PLoS One. 2016 Oct 20;11(10):e0164015.

    2015年

    1. Watatani H, Yamasaki H, Maeshima Y, Nasu T, Hinamoto N, Ujike H, Sugiyama H, Sakai Y, Tanabe K, Makino H. ONO-1301, a sustained-release prostacyclin analogue, ameliorates the renal alteration in a mouse type 2 diabetes model possibly through its protective effects on mesangial cells. Acta Medica Okayama. 2015 69(1):1-15.
    2. Uchida HA, Uchida H, Wada J, Acute Effect of Aliskiren on Smoking-Induced Endothelial Function in Smoker. J Cardiovasc Med Cardiol 2(1): 013-016. 2015
    3. Ujike-Omori H, Maeshima Y, Kinomura M, Tanabe K, Mori K, Watatani H, Hinamoto N, Sugiyama H, Sakai Y, Morimatsu H, Makino H. The urinary levels of prostanoid metabolites predict acute kidney injury in heterogeneous adult Japanese ICU patients: a prospective observational study. Clin Exp Nephrol. 2015 Dec;19(6):1024-36.
    4. Okuyama Y, Uchida HA, Tenta M, Nunoue T, Umebayashi R, Morinaga H, Kitamura S, Maeshima Y, Sugiyama H, Wada J. Autoimmune pancreatitis and minimal change nephrotic syndrome: an unusual association? Nephrology (Carlton). 2015 Mar;20(3):225-6.
    5. Sugimoto K, Toda Y, Iwasaki T, Shimizu K, Kanazawa T, Muto N, Kawase H, Morimatsu H, Morita K, Maeshima Y, Mori K, Sano S. Urinary Albumin Levels Predict Development of Acute Kidney Injury After Pediatric Cardiac Surgery: A Prospective Observational Study. J Cardiothorac Vasc Anesth. 2015 May 22. pii: S1053-0770(15)00504-2.
    6. Fujiwara H, Gobara H, Hiraki T, Iguchi T, Uchida HA, Kanazawa S. Retrograde Renal Ablation via the Renal Vein as a New Treatment Option for Renovascular Hypertension. J Vasc Interv Radiol. 2015 Jun;26(6):807-8.
    7. Tenta M, Uchida HA, Nunoue T, Umebayashi R, Okuyama Y, Kitagawa M, Maeshima Y, Sugiyama H, Makino H, Successful treatment by mycophenolate mofetil in a patient with focal segmental glomerulosclerosis associated with posterior reversible encephalopathy syndrome. Clin Exp Nephrol case report 2015 Nov;4(2):190-195.
    8. Wada K, Wada Y, Uchida HA, Tsuruoka S, Effects of Lanthanum Carbonate vs. Calcium Carbonate on Vascular Stiffness and Bone Mineral Metabolism in Hemodialysis Patients with Type 2 Diabetes Mellitus: Randomized Controlled Trial. Int J Nephrol Renovasc Dis. 2015 Aug 26;8:111-8.
    9. Saito Y, Nakamura K, Yoshida M, Sugiyama H, Ohe T, Kurokawa J, Furukawa T, Takano M, Nagase S, Morita H, Kusano KF, Ito H. Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker. PLoS One. 2015 Sep 18;10(9):e0138193.

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